Mouli Ganguli was born to a Bengali family in Kolkata. She has done her graduation in Science from University of Calcutta, and later moved to hotel management in 1993. She then went on to gain a degree in Mass Communication and left it midway when she started getting modeling offers.
Mouli is a famous television actress, currently seen on the show Kya Hua Tera Vadaa. The actress has also been seen in many television and print advertisements for products like Ariel, Rin, Pears, Asian Paints, Sonam Quartz and many more.
She got married to her boyfriend and her co-star from the show Kahin Kisii Roz Mazhar Sayyed and also appeared on Nach Baliye with him.